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瓣膜异种移植和瓣膜异种生物假体:过去、现在和未来。

Valvular xenograft and valvular xenobioprosthesis: Past, present, and future.

作者信息

Carpentier A

出版信息

Adv Cardiol. 1980;27:281-93. doi: 10.1159/000383994.

DOI:10.1159/000383994
PMID:7446289
Abstract

At the present time, glutaraldehyde-preserved porcine valves appear to be a reasonable alternative in valvular replacement. The expected durability limit of 8-15 years with the models currently commercially available is counterbalanced by a lower risk of acute complications; particularly thromboembolism. This allows the patient to be free from drugs and related problems. Our opinion is that the patient should take part in choosing between a bioprosthesis and a mechanical prosthesis. This critical choice will depend upon the relative importance for each individual of an improved quality of life with a bioprosthesis versus a lower risk of reoperation with a mechanical valve.

摘要

目前,戊二醛保存的猪瓣膜似乎是瓣膜置换术中一种合理的选择。当前市面上的型号预期耐用年限为8至15年,这一期限与较低的急性并发症风险相权衡,尤其是血栓栓塞风险。这使得患者无需服药及面临相关问题。我们的观点是,患者应参与生物瓣膜和机械瓣膜的选择。这一关键选择将取决于生物瓣膜带来的生活质量改善与机械瓣膜再次手术风险较低对每个个体的相对重要性。

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