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对北爱尔兰两个独立的先天性畸形常规记录系统所识别出的神经管缺陷进行的比较。

A comparison of neural tube defects identified by two independent routine recording systems for congenital malformations in Northern Ireland.

作者信息

Nevin N C, McDonald J R, Walby A L

出版信息

Int J Epidemiol. 1978 Dec;7(4):319-21. doi: 10.1093/ije/7.4.319.

Abstract

The efficiency of two systems for recording congenital malformations has been compared; one system, the Registrar General's Congenital Malformation Notification, is based on registering all malformed infants, and the other, the Child Health System, records all births. In Northern Ireland for three years [1974--1976], using multiple sources of ascertainment, a total of 686 infants with neural tube defects was identified among 79 783 live and stillbirths. The incidence for all neural tube defects in 8 60 per 1 000 births. The Registrar General's Congenital Malformation Notification System identified 83.6% whereas the Child Health System identified only 63.3% of all neural tube defects. Both systems together identified 86.2% of all neural tube defects. The two systems are suitable for monitoring of malformations and the addition of information from the Genetic Counselling Clinics would enhance the data for epidemiological studies.

摘要

对两种记录先天性畸形的系统的效率进行了比较;一种系统是总登记官的先天性畸形通报系统,该系统基于对所有畸形婴儿进行登记,另一种系统是儿童健康系统,记录所有出生情况。在北爱尔兰的三年时间里(1974 - 1976年),利用多种确定来源,在79783例活产和死产中,共确认了686例患有神经管缺陷的婴儿。所有神经管缺陷的发病率为每1000例出生中有8.60例。总登记官的先天性畸形通报系统识别出了所有神经管缺陷的83.6%,而儿童健康系统仅识别出了63.3%。两种系统共同识别出了所有神经管缺陷的86.2%。这两种系统都适用于监测畸形情况,并且增加来自遗传咨询诊所的信息将增强流行病学研究的数据。

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