Peters M, Mackay I R, Buckley J D
Am J Pathol. 1980 Dec;101(3):647-56.
An analysis was made of survival times and causes of death of patients given local irradiation in small dosage during 1948--1960. The study involved 61 patients with peptic ulcers in whom hyperacidity was treated by partial gastrectomy and gastric irradiation, and their mortality was compared with that of 61 age- and sex-matched gastrectomized but nonirradiated control patients. For both groups the survival rates were related to "normal population" survival rates calculated from age-, sex- and year-specific mortality rates for the population of Victoria. Ten years after irradiation the relative survival rates of the irradiated and control groups began to diverge, due to more deaths than expected in the irradiated group. The irradiated group had a significantly increased number of deaths due to cancer, particularly carcinoma of the stomach, as well as an increase in deaths not caused by cancer. The mortality of the nonirradiated control patients was not significantly greater than that of the normal population.
对1948年至1960年间接受小剂量局部照射的患者的生存时间和死亡原因进行了分析。该研究涉及61例消化性溃疡患者，他们通过胃部分切除术和胃部照射治疗胃酸过多，并将其死亡率与61例年龄和性别匹配的接受胃切除术但未接受照射的对照患者的死亡率进行比较。对于两组患者，生存率均与根据维多利亚州人口的年龄、性别和年份特异性死亡率计算出的“正常人群”生存率相关。照射十年后，照射组和对照组的相对生存率开始出现差异，原因是照射组的死亡人数超过预期。照射组因癌症导致的死亡人数显著增加，尤其是胃癌，同时非癌症导致的死亡人数也有所增加。未接受照射的对照患者的死亡率并不显著高于正常人群。
