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芬兰青少年的过敏性疾病与即时皮肤试验反应性

Allergic disorders and immediate skin test reactivity in Finnish adolescents.

作者信息

Haahtela T, Heiskala M, Suoniemi I

出版信息

Allergy. 1980 Jul;35(5):433-41. doi: 10.1111/j.1398-9995.1980.tb01790.x.

Abstract

We studied the prevalence of allergic disorders in an unselected group of 708 adolescents aged 15-17 years. All subjects were physically examined and interviewed by the authors. The prevalence of past or present asthma was 5.7% in boys and 3.1% in girls. The figures for hay fever were 14% and 8%, and for atopic dermatitis (including allergic urticaria) 25% and 30%, respectively. In 24% of all symptomatic subjects, the condition had not been active during the year preceding the study. The sex difference in the prevalence of hay fever was significant. It is associated with higher immediate skin test reactivity in boys. A progressive increase in the frequency of allergic disorders was observed with increasing number of positive skin reactions in both boys and girls. Respiratory allergy was closely related to a positive skin test: 87% of the asthmatics and 83% of all those with allergic rhinitis exhibited at least one positive skin reaction. For atopic dermatitis the association was less pronounced. Nineteen per cent of the population studied had a positive symptom history and a positive skin test to pollens, animal epithelia or dusts indicating a clinically significant relationship. However, 39% of the 346 subjects with a positive skin test, including some with a large number of positive reactions, were completely asymptomatic.

摘要

我们对一组708名年龄在15至17岁之间未经过筛选的青少年进行了过敏性疾病患病率的研究。所有受试者均由作者进行了体格检查和访谈。过去或现在患有哮喘的患病率在男孩中为5.7%,在女孩中为3.1%。花粉热的患病率分别为14%和8%,特应性皮炎(包括过敏性荨麻疹)的患病率分别为25%和30%。在所有有症状的受试者中,24%的人在研究前一年病情未发作。花粉热患病率的性别差异显著。这与男孩较高的即时皮肤试验反应性有关。在男孩和女孩中,随着皮肤反应阳性数量的增加,过敏性疾病的发生率逐渐上升。呼吸道过敏与皮肤试验阳性密切相关:87%的哮喘患者和83%的过敏性鼻炎患者至少有一项皮肤反应阳性。对于特应性皮炎,这种关联不太明显。19%的研究人群有阳性症状史且对花粉、动物上皮或灰尘的皮肤试验呈阳性,表明存在临床显著关系。然而,在346名皮肤试验阳性的受试者中,39%的人完全无症状,其中包括一些有大量阳性反应的人。

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