高比放射性氚标记人β-内啡肽的制备及其性质
Preparation and properties of tritiated human beta-endorphin with high specific radioactivity.
作者信息
Houghten R A, Li C H
出版信息
Int J Pept Protein Res. 1978 Nov;12(5):325-6. doi: 10.1111/j.1399-3011.1978.tb02904.x.
Abstract
Tritiated human beta-endorphin, specifically labelled at Tyr27, has been prepared with 50 Ci/mmol. Various physicochemical investigations indicated that tritiated peptide is identical with the native betah-endorphin. In addition, opiate activity of the tritiated product possesses the same potency as the native peptide.
摘要
已制备出在酪氨酸27处特异性标记的氚化人β-内啡肽，其比活度为50居里/毫摩尔。各种物理化学研究表明，氚化肽与天然β-内啡肽相同。此外，氚化产物的阿片样物质活性与天然肽具有相同的效力。
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