Abbushi W, Herkt G, Speckner E, Birk M
Anaesthesist. 1980 Oct;29(10):521-4.
Studies about ICP-variations of brain-injured patients under artificial ventilation seem to become important, since most of those patients, especially those with various additional injuries, do not breathe spontaneously. After having ventilated 10 patients with endexpiratory pressure from 0 to 10 cm H2O, significant ICP-rises could be monitored. A significant linear ICP-decrease could be induced by lifting the upper part of the body in corresponding linear rates. If applied in clinical work, the combination of these two methods we studied, seems to mean some sort of compensation of any ICP-changes during artificial ventilation. Therefore the indication for peep ventilation of brain-injured patients can be put less limited by ventilation-caused ICP-rises.
对于人工通气下脑损伤患者的颅内压（ICP）变化进行研究似乎变得很重要，因为这些患者中的大多数，尤其是那些伴有各种附加损伤的患者，无法自主呼吸。在对10例患者进行呼气末压力从0至10厘米水柱的通气后，可监测到颅内压显著升高。以相应的线性速率抬高身体上部可引起颅内压显著线性下降。如果将我们所研究的这两种方法结合应用于临床工作，似乎意味着在人工通气期间对任何颅内压变化的某种补偿。因此，脑损伤患者进行呼气末正压通气（PEEP）的指征受通气引起的颅内压升高的限制可减少。
