Bauer B S, Lewis V L
Ann Plast Surg. 1980 Sep;5(3):222-6. doi: 10.1097/00000637-198009000-00008.
Malignant degeneration of sebaceous and other epidermoid cysts in uncommon, but it does occur in approximately 2.2% of cysts examined. It should be suspected in patients with atypical appearance or a history of cyst recurrence. All cysts should be examined histologically and the histological grade carefully noted. This paper reports a well-differentiated squamous cell carcinoma arising in an epidermoid cyst. Wide excision was performed, including superficial parotidectomy, because of histological evidence of extension beyond the cyst. Based on the literature, recurrence or metastasis of our patient's tumor appears unlikely.
皮脂腺囊肿和其他表皮样囊肿的恶性变并不常见，但在所检查的囊肿中约2.2%确实会发生。对于外观不典型或有囊肿复发史的患者应怀疑有恶性变。所有囊肿均应进行组织学检查，并仔细记录组织学分级。本文报告1例发生于表皮样囊肿的高分化鳞状细胞癌。由于组织学证据显示肿瘤超出囊肿范围，故行广泛切除，包括浅叶腮腺切除术。根据文献，该患者肿瘤复发或转移的可能性似乎不大。
