微小巴贝斯虫感染蒙古沙鼠的化学疗法。
Chemotherapy of Babesia microti infections in Mongolian Jirds.
作者信息
Ruebush T K, Contacos P G, Steck E A
出版信息
Antimicrob Agents Chemother. 1980 Aug;18(2):289-91. doi: 10.1128/AAC.18.2.289.
Abstract
For identifying drugs which might be effective in the treatment of human Babesia microti infections, 20 selected antiprotozoal agents or combinations of agents were tested for activity against B. microti in Mongolian jirds (meriones unguiculatus). 4-Methyl-primaquine and aromatic diamidines, including diminazene and pentamidine, were the most effective compounds tested.
摘要
为了确定可能有效治疗人类微小巴贝斯虫感染的药物，对20种选定的抗原生动物药物或药物组合进行了测试，以检测其对蒙古沙鼠（长爪沙鼠）体内微小巴贝斯虫的活性。4-甲基伯氨喹和芳香族二脒类药物，包括地克珠利和喷他脒，是测试中最有效的化合物。
相似文献
1
Chemotherapy of Babesia microti infections in Mongolian Jirds.微小巴贝斯虫感染蒙古沙鼠的化学疗法。
Antimicrob Agents Chemother. 1980 Aug;18(2):289-91. doi: 10.1128/AAC.18.2.289.
2
Activity of atovaquone against Babesia microti in the Mongolian gerbil, Meriones unguiculatus.阿托伐醌对长爪沙鼠（Meriones unguiculatus）体内微小巴贝斯虫的活性。
J Parasitol. 1999 Aug;85(4):723-8.
3
Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo.新型二脒类化合物对体外巴贝西虫和体内微小巴贝西虫具有活性。
Antimicrob Agents Chemother. 2011 Jul;55(7):3439-45. doi: 10.1128/AAC.01482-10. Epub 2011 May 2.
4
In vivo assays for drug resistance in Babesia divergens using the Mongolian gerbil, Meriones unguiculatus.利用长爪沙鼠（Meriones unguiculatus）对分歧巴贝斯虫进行体内耐药性检测。
Res Vet Sci. 1992 Jan;52(1):126-8. doi: 10.1016/0034-5288(92)90073-b.
5
Chemotherapy of Babesia divergens in the gerbil, Meriones unguiculatus.沙土鼠（长爪沙鼠）中分歧巴贝斯虫的化学疗法。
Res Vet Sci. 1983 Nov;35(3):318-24.
6
Antiprotozoal treatment of canine babesiosis.犬巴贝斯虫病的抗原虫治疗。
Vet Parasitol. 2018 Apr 30;254:58-63. doi: 10.1016/j.vetpar.2018.03.001. Epub 2018 Mar 7.
7
Inhibitory effects of 19 antiprotozoal drugs and antibiotics on Babesia microti infection in BALB/c mice.19种抗原生动物药物和抗生素对BALB/c小鼠微小巴贝斯虫感染的抑制作用。
J Infect Dev Ctries. 2015 Sep 27;9(9):1004-10. doi: 10.3855/jidc.5500.
8
Evaluation of selected antiprotozoal drugs in the Babesia microti-hamster model.在微小巴贝斯虫-仓鼠模型中对选定抗寄生虫药物的评估。
Antimicrob Agents Chemother. 1997 Jan;41(1):91-4. doi: 10.1128/AAC.41.1.91.
9
Misdiagnosis of Babesiosis as Malaria, Equatorial Guinea, 2014.2014 年赤道几内亚将巴贝虫病误诊为疟疾。
Emerg Infect Dis. 2018 Aug;24(8):1588-1589. doi: 10.3201/eid2408.180180.
10
Combination of Clofazimine and Atovaquone as a Potent Therapeutic Regimen for the Radical Cure of Babesia microti Infection in Immunocompromised Hosts.氯法齐明与阿托伐醌联合应用于免疫抑制宿主巴贝虫微小亚种根治的强效治疗方案。
J Infect Dis. 2022 Jan 18;225(2):238-242. doi: 10.1093/infdis/jiab537.
引用本文的文献
1
Do Hosts Share a Blood Group System Gene Ortholog, Which Could Generate an Erythrocyte Antigen That Is Essential for Parasite Invasion?宿主是否共享一个血型系统基因直系同源物，该直系同源物是否能产生寄生虫入侵所必需的红细胞抗原？
Trop Med Infect Dis. 2024 Aug 26;9(9):195. doi: 10.3390/tropicalmed9090195.
2
efficacy of next-generation dihydrotriazines and biguanides against babesiosis and malaria parasites.新一代二氢三嗪和双胍类药物抗巴贝斯虫和疟原虫的疗效。
Antimicrob Agents Chemother. 2024 Sep 4;68(9):e0042324. doi: 10.1128/aac.00423-24. Epub 2024 Aug 13.
3
Efficacy of the Antimalarial MMV390048 against Infection Reveals Phosphatidylinositol 4-Kinase as a Druggable Target for Babesiosis.抗疟药 MMV390048 抗 感染的疗效揭示了磷脂酰肌醇 4-激酶是巴贝西虫病的可用药靶标。
Antimicrob Agents Chemother. 2022 Sep 20;66(9):e0057422. doi: 10.1128/aac.00574-22. Epub 2022 Aug 4.
4
Treatment of Human Babesiosis: Then and Now.人类巴贝斯虫病的治疗：过去与现在
Pathogens. 2021 Sep 1;10(9):1120. doi: 10.3390/pathogens10091120.
5
Activities of artesunate-based combinations and tafenoquine against Babesia bovis in vitro and Babesia microti in vivo.青蒿琥酯联合用药和他非诺喹对牛巴贝斯虫的体外活性和微小巴贝斯虫的体内活性。
Parasit Vectors. 2020 Jul 20;13(1):362. doi: 10.1186/s13071-020-04235-7.
6
Novel diamidines with activity against Babesia divergens in vitro and Babesia microti in vivo.新型二脒类化合物对体外巴贝西虫和体内微小巴贝西虫具有活性。
Antimicrob Agents Chemother. 2011 Jul;55(7):3439-45. doi: 10.1128/AAC.01482-10. Epub 2011 May 2.
7
Evaluation of selected antiprotozoal drugs in the Babesia microti-hamster model.在微小巴贝斯虫-仓鼠模型中对选定抗寄生虫药物的评估。
Antimicrob Agents Chemother. 1997 Jan;41(1):91-4. doi: 10.1128/AAC.41.1.91.
本文引用的文献
1
Babesiosis in a Massachusetts resident.一名马萨诸塞州居民患巴贝斯虫病。
N Engl J Med. 1970 Oct 15;283(16):854-6. doi: 10.1056/NEJM197010152831607.
2
Entopolypoides macaci (Babesiidae) in Macaca mulatta.
J Parasitol. 1974 Oct;60(5):844-7.
3
The antileishmanial activity of lepidines.勒皮定的抗利什曼原虫活性。
Am J Trop Med Hyg. 1978 Jul;27(4):751-7. doi: 10.4269/ajtmh.1978.27.751.
4
Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.
Ann Intern Med. 1978 Feb;88(2):200-2. doi: 10.7326/0003-4819-88-2-200.
5
Neurologic complications following the treatment of human Babesia microti infection with diminazene aceturate.
Am J Trop Med Hyg. 1979 Mar;28(2):184-9. doi: 10.4269/ajtmh.1979.28.184.
6
Human babesiosis on Nantucket Island. Evidence for self-limited and subclinical infections.
N Engl J Med. 1977 Oct 13;297(15):825-7. doi: 10.1056/NEJM197710132971511.
7
Experimental Babesia microti infections in non-splenectomized Macaca mulatta.
J Parasitol. 1979 Feb;65(1):144-6.
Zotero 插件