Estler C J, Böcker R, Schinzel W
Arch Int Pharmacodyn Ther. 1980 Sep;247(1):39-42.
The effect of naftidrofuryl (40 micrograms/g i.p.) on the ATP, phosphocreatine (PC), glycogen, lactate and pyruvate contents of the heart during respiratory arrest and postanoxic recovery was studied in mice. Naftidrofuryl increased he PC-content of the heart of normal mice. It did not prevent the metabolic changes brought about by 1 min anoxia but accelerated the post anoxic recovery of the depleted PC-content on account of delayed replenishment of the reduced glycogen stores. The changes in the ATP, lactate and pyruvate contents were not affected.
研究了萘呋胺酯（腹腔注射40微克/克）对小鼠呼吸停止及缺氧后恢复过程中心脏三磷酸腺苷（ATP）、磷酸肌酸（PC）、糖原、乳酸和丙酮酸含量的影响。萘呋胺酯可增加正常小鼠心脏的PC含量。它不能防止1分钟缺氧引起的代谢变化，但由于糖原储备减少的补充延迟，加速了缺氧后耗尽的PC含量的恢复。ATP、乳酸和丙酮酸含量的变化未受影响。
