环亮氨酸、天冬氨酸和谷氨酸膦酸类似物的体外细胞生长抑制活性
Cytostatic activity in vitro of cycloleucine, aspartic acid and glutamic acid phosphonic analogues.
作者信息
Duś D, Salwa J, Mastalerz P
出版信息
Arch Immunol Ther Exp (Warsz). 1980;28(3):433-8.
PMID:7447648
Abstract
Cytostatic activity of 18 new phosphonic acid derivatives of cycloleucine, aspartic acid and glutamic acid was tested against human KB and mouse L1210s leukemia cell lines in vitro. The tests were performed according to international protocol 1.600 for screening of chemical agents against tissue culture system. Four of the tested compounds revealed their cytostatic activity at the dose 10 micrograms/ml.
摘要
对环亮氨酸、天冬氨酸和谷氨酸的18种新型膦酸衍生物针对人KB细胞系和小鼠L1210白血病细胞系进行了体外细胞生长抑制活性测试。测试按照针对组织培养系统的化学药剂筛选国际协议1.600进行。4种受试化合物在剂量为10微克/毫升时显示出细胞生长抑制活性。
Zotero 插件