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[节前激活对大鼠颈上神经节中与α-银环蛇毒素相关的烟碱型胆碱能受体的影响]

[Effect of preganglionic activation on nicotinic cholinergic receptors linked to alpha-bungarotoxin in the rat superior cervical ganglion].

作者信息

Fumagalli L, De Renzis G

出版信息

Boll Soc Ital Biol Sper. 1980 Jul 30;56(14):1504-6.

PMID:7448049
Abstract

alpha-Bungarotoxin binds to nicotinic cholinergic sites in the rat superior cervical ganglion. In physiological conditions the receptors are relatively independent upon preganglionic signals, as suggested by experiments of preganglionic denervation. In the present paper we show that the receptors are also uneffected by the afferent nerve fibres when preganglionic activation is induced by Reserpine administration or by cold exposure.

摘要

α-银环蛇毒素与大鼠颈上神经节中的烟碱型胆碱能位点结合。在生理条件下,如节前去神经实验所示,这些受体相对独立于节前信号。在本文中,我们表明,当通过给予利血平或冷暴露诱导节前激活时,这些受体也不受传入神经纤维的影响。

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