[暴露于双重应激（干热-禁食）的大鼠心脏中苹果酸脱氢酶和谷氨酸脱氢酶的变化。III]

[Modification of malate dehydrogenase and glutamate dehydrogenase in hearts of rats exposed to a double stress (dry heat - fasting). III].

作者信息

Gulisano G, Inserra A, Pignataro P, Bellia M, Spanti D, Mancuso S

出版信息

Boll Soc Ital Biol Sper. 1980 Apr 30;56(8):763-7.

Abstract

MDH and GLDH activity modifications have been studied in heart homogenized of rats exposed to double stress (dry heat and starvation). MDH activity shows statistically significant variations only after 72 hours. This induces to suspect a decrease of energetic metabolism due to a probable substratum lack. GLDH activity shows a statistically significant decrease after 24 hours, and this decrease increases after 72 hours. This behaviour could be explained by an acclimatization reaction of such an amount to delete the hunger effect on protein catabolism.

摘要

已经对暴露于双重应激（干热和饥饿）的大鼠心脏匀浆中的苹果酸脱氢酶（MDH）和谷氨酸脱氢酶（GLDH）活性变化进行了研究。MDH活性仅在72小时后显示出统计学上的显著变化。这使人怀疑由于可能的底物缺乏导致能量代谢下降。GLDH活性在24小时后显示出统计学上的显著下降，并且在72小时后这种下降加剧。这种行为可以通过这样一种量的适应反应来解释，以消除饥饿对蛋白质分解代谢的影响。

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