Fletcher C H
J Epidemiol Community Health (1978). 1978 Dec;32(4):282-8. doi: 10.1136/jech.32.4.282.
Until the 1960's there was great confusion, both within and between countries, on the meaning of diagnostic terms such as emphysema, asthma, and chronic brochitis. Proposals made by a group of British doctors in 1959 gradually received widespread acceptance but in recent years some new problems have developed. These include difficulties in the definition of airflow obstruction, recognition that what used to be regarded as a single disease, chronic bronchitis, comprises at least two distinct pathological processes, and uncertainty about the degree of variability which distinguishes asthmatic from more persistent forms of airflow obstruction. These are all problems which could be solved by continuance of appropriate research and of riqorous attention to the principles which determine accurate and acceptable definitions of disease.
直到20世纪60年代,在各国国内以及国与国之间,对于诸如肺气肿、哮喘和慢性支气管炎等诊断术语的含义存在极大的混淆。1959年一群英国医生提出的建议逐渐得到广泛认可,但近年来又出现了一些新问题。这些问题包括气流受限定义方面的困难,认识到过去被视为单一疾病的慢性支气管炎至少包含两种不同的病理过程,以及区分哮喘与更持续性气流受限形式的变异性程度的不确定性。所有这些问题都可以通过持续进行适当的研究以及严格遵循确定准确且可接受的疾病定义的原则来解决。