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[再生障碍性贫血患者单核细胞在扩散小室中的培养(作者译)]

[Culture of mononuclear cells from patients with aplastic anemia in diffusion chambers (author's transl)].

作者信息

Böning L, Lau B, Wilmanns W

出版信息

Blut. 1980 Dec;41(6):445-50. doi: 10.1007/BF01007769.

DOI:10.1007/BF01007769
PMID:7448431
Abstract

The growth of mononuclear human peripheral blood cells from five patients with aplastic anemia (AA) was tested in diffusion chambers over a period of 13 days. Considerable differences were seen in the total cell number compared with controls. The total cell number of three patients with AA was markedly lower than in the control group (eight controls). The differentiation of the cells showed considerable differences in the growth patterns of the lymphocytes and in granulopoiesis; in three of five patients with AA no granulopoiesis was observed.

摘要

在扩散小室中对5例再生障碍性贫血(AA)患者的人外周血单个核细胞进行了为期13天的培养。与对照组相比,细胞总数存在显著差异。3例AA患者的细胞总数明显低于对照组(8例对照)。细胞分化在淋巴细胞生长模式和粒细胞生成方面表现出显著差异;5例AA患者中有3例未观察到粒细胞生成。

相似文献

1
[Culture of mononuclear cells from patients with aplastic anemia in diffusion chambers (author's transl)].[再生障碍性贫血患者单核细胞在扩散小室中的培养(作者译)]
Blut. 1980 Dec;41(6):445-50. doi: 10.1007/BF01007769.
2
Granulopoiesis in childhood aplastic anemia.儿童再生障碍性贫血中的粒细胞生成
J Pediatr. 1976 May;88(5):790-4. doi: 10.1016/s0022-3476(76)81116-x.
3
[Studies on the subpopulations of peripheral lymphocytes of the patients with idiopathic aplastic anemia (author's transl)].
Rinsho Ketsueki. 1973 Nov;14(11):1075-9.
4
[Studies on the lymphocytes of the patients with aplastic anemia (author's transl)].再生障碍性贫血患者淋巴细胞的研究(作者译)
Nihon Ketsueki Gakkai Zasshi. 1975 Oct;38(5):557-63.
5
A pathogenetic link between aplastic anemia and paroxysmal nocturnal hemoglobinuria is suggested by a high frequency of aplastic anemia patients with a deficiency of phosphatidylinositol glycan anchored proteins.再生障碍性贫血患者中磷脂酰肌醇聚糖锚定蛋白缺乏的频率较高,提示再生障碍性贫血与阵发性夜间血红蛋白尿之间存在发病机制上的联系。
Exp Hematol. 1995 Jan;23(1):81-7.
6
[The action of antilymphocyte serum in severe aplastic anemia (author's transl)].抗淋巴细胞血清在严重再生障碍性贫血中的作用(作者译)
Nouv Presse Med. 1978 Feb 11;7(6):439-43.
7
[The lymphocytes of the patients with hypoplastic anemia (author's transl)].再生障碍性贫血患者的淋巴细胞(作者译)
Rinsho Ketsueki. 1975 Aug;16(8):763-7.
8
Recovery of hematologic competence without engraftment following attempted bone marrow transplantation for aplastic anemia: Report of a case with diffusion chamber studies.再生障碍性贫血患者尝试进行骨髓移植后未发生植入但血液学功能恢复:1例伴有扩散盒研究的病例报告
Exp Hematol. 1977 Jan;5(1):51-8.
9
[Role of Th1 cell in the pathogenesis of aplastic anemia].[辅助性T细胞1在再生障碍性贫血发病机制中的作用]
Zhonghua Xue Ye Xue Za Zhi. 2002 Nov;23(11):574-7.
10
IFN-gamma is not the only mediator of suppressed myelopoiesis produced by mononuclear cells from aplastic anemia patients.γ干扰素并非再生障碍性贫血患者单核细胞产生的骨髓生成抑制的唯一介质。
J Biol Regul Homeost Agents. 1987 Jan-Mar;1(1):37-44.

本文引用的文献

1
Bone-marrow microenvironment defect in congenital hypoplastic anemia.
N Engl J Med. 1980 Jun 12;302(24):1321-7. doi: 10.1056/NEJM198006123022401.
2
In vitro granulocytic colony-forming potential of bone marrow from patients with granulocytopenia and aplastic anemia.粒细胞减少症和再生障碍性贫血患者骨髓的体外粒细胞集落形成潜力。
Proc Soc Exp Biol Med. 1971 Jul;137(3):917-20. doi: 10.3181/00379727-137-35693.
3
Formation of granulocytes and macrophages in diffusion chamber cultures of mouse blood leucocytes.小鼠血液白细胞扩散室培养中粒细胞和巨噬细胞的形成
Scand J Haematol. 1970;7(4):279-88. doi: 10.1111/j.1600-0609.1970.tb01899.x.
4
Proliferation of human bone marrow cells in diffusion chambers implanted into normal or irradiated mice.植入正常或受辐照小鼠体内的扩散小室中人类骨髓细胞的增殖。
Blood. 1972 Aug;40(2):163-73.
5
Growth of human leukaemic peripheral blood cells in diffusion chambers.
Eur J Cancer (1965). 1974 Sep;10(9):579-89. doi: 10.1016/0014-2964(74)90046-2.
6
Isolation of mononuclear cells and granulocytes from human blood. Isolation of monuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g.从人血中分离单核细胞和粒细胞。通过一次离心分离单核细胞,通过离心和1g沉降相结合的方法分离粒细胞。
Scand J Clin Lab Invest Suppl. 1968;97:77-89.
7
Granulopoiesis in childhood aplastic anemia.儿童再生障碍性贫血中的粒细胞生成
J Pediatr. 1976 May;88(5):790-4. doi: 10.1016/s0022-3476(76)81116-x.
8
The growth of human bone marrow in diffusion chambers.人骨髓在扩散小室中的生长。
Br J Haematol. 1975 Jan;29(1):89-97. doi: 10.1111/j.1365-2141.1975.tb01802.x.
9
Editorial: The pathogenesis of aplastic anemia: a defective pluripotent hematopoietic stem cell with inappropriate balance of differentiation and self-replication.社论:再生障碍性贫血的发病机制:一种具有分化与自我复制平衡失调的缺陷性多能造血干细胞。
Blood. 1976 Jul;48(1):71-6.
10
[Culture of leukocytes of patients with hairy cell leukaemia in the diffusion chamber (author's transl)].
Blut. 1977 Aug 29;35(2):103-13. doi: 10.1007/BF00996290.