Sears M E, Olson K B
Cancer. 1980 Dec 15;46(12 Suppl):2928-9. doi: 10.1002/1097-0142(19801215)46:12+<2928::aid-cncr2820461437>3.0.co;2-q.
Extramural evaluation of 385 clinical responses of advanced breast cancer agreed with the investigators' interpretation in 306 cases (79%) and disagreed in 19 cases (5%). Sixty cases (165%) were nonevaluable because of inadequate documentation. The rate of agreement with the seven groups of investigators ranged from 70% to 92%. The investigators had submitted their case material from review in preparation for their reporting on the relationship between the estrogen receptor content of breast cancer tissue and the response to cytotoxic chemotherapy. The reviewers used only objective criteria for their evaluation. They urge that clinical investigators report their findings quantitatively whenever possible and use standard methods of documentation.U
对385例晚期乳腺癌临床反应的校外评估中，306例（79%）与研究者的解释一致，19例（5%）不一致。60例（16%）因记录不充分而无法评估。与七组研究者的一致率在70%至92%之间。研究者提交了他们用于回顾的病例材料，以准备报告乳腺癌组织雌激素受体含量与细胞毒性化疗反应之间的关系。评审者仅使用客观标准进行评估。他们敦促临床研究者尽可能定量报告研究结果，并采用标准的记录方法。
