Nagaoka S, Yamanaka E, Nakazawa Y, Katano F
Clin Ther. 1980;3(2):137-42.
Samples of sputum were collected from ten patients with chronic respiratory diseases following treatment with Varidase (streptodornase and streptokinase) buccal tablets, four tablets per day for a period of seven days, and were compared with specimens obtained before the therapy in terms of rheological and cytochemical parameters. The study revealed a tendency for the respiratory secretion to show a lowered yield point and a decrease in mucous fibers after the therapy, thus suggesting, to some extent, the efficacy of the drug as an expectorant.
从10名慢性呼吸道疾病患者中采集痰液样本，这些患者在用Varidase（链道酶和链激酶）颊含片治疗后，每天4片，持续7天，并将治疗后的样本与治疗前获取的样本在流变学和细胞化学参数方面进行比较。研究显示，治疗后呼吸道分泌物有屈服点降低和黏液纤维减少的趋势，从而在一定程度上表明该药物作为祛痰剂的疗效。
