七十岁以上人群的循环免疫球蛋白E水平。

Circulating IgE levels in the over-seventies.

作者信息

Merrett T G, Burr M L, Saint Leger A S, Merrett J

出版信息

Clin Allergy. 1980 Jul;10(4):433-9. doi: 10.1111/j.1365-2222.1980.tb02126.x.

DOI:10.1111/j.1365-2222.1980.tb02126.x

Abstract

In a normal population aged over 70 years the geometric mean IgE value of 30.6 u/ml was not significantly different from that obtained previously in a similar epidemiological survey of a population aged 20-44 years. However, in the older population we have noted a significant sex difference-38.6 u/ml for males against 27.2 u/ml for females-which was only apparent in the atopic subjects of the younger population. There have been some other reports that IgE levels decrease with age, and possible reasons for these differences with our own results are discussed.

摘要

在70岁以上的正常人群中，几何平均免疫球蛋白E（IgE）值为30.6单位/毫升，与之前在一项针对20 - 44岁人群的类似流行病学调查中获得的值没有显著差异。然而，在老年人群中，我们注意到存在显著的性别差异——男性为38.6单位/毫升，女性为27.2单位/毫升——这种差异仅在年轻人群的特应性受试者中明显。还有其他一些报告称IgE水平会随着年龄增长而下降，本文讨论了这些差异与我们自己研究结果不同的可能原因。