大鼠门腔静脉分流术后的肝鸟氨酸氨基转移酶

Hepatic ornithine aminotransferase in the rat after portacaval shunt.

作者信息

Colombo J P, Bachmann C

出版信息

Enzyme. 1980;25(5):297-303. doi: 10.1159/000459270.

Abstract

L-Ornithine (2-oxoacid aminotransferase, OKT) has been determined in the livers of portacaval shunt (PCS) rats, submitted to different diets, influencing blood brain amino acid transport. OKT activity was not greatly influenced by PCS. An in vivo stimulatory effect by branched chain amino acids and arginine could not be observed or confirmed by amino acid analysis in liver tissue. However, after the addition of glucose to the diet, a significant drop of OKT activity occurred.

摘要

已对接受不同饮食、影响血脑氨基酸转运的门腔分流术（PCS）大鼠的肝脏进行了L-鸟氨酸（2-氧代酸氨基转移酶，OKT）测定。OKT活性受PCS的影响不大。在肝脏组织的氨基酸分析中未观察到或证实支链氨基酸和精氨酸的体内刺激作用。然而，在饮食中添加葡萄糖后，OKT活性显著下降。