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吗啡与电针:大鼠牙髓刺激后对皮质诱发电位影响的比较

Morphine and electroacupuncture: comparison of the effects on the cortical evoked responses after tooth pulp stimulation in rats.

作者信息

Iriki A, Toda K

出版信息

Eur J Pharmacol. 1980 Nov 7;68(1):83-7. doi: 10.1016/0014-2999(80)90066-7.

Abstract

The effects of morphine and electroacupuncture on the cortical evoked responses after tooth pulp stimulation were investigated in rats. Morphine suppressed these responses more strongly in secondary somatosensory areas than those in primary somatosensory areas, while electroacupuncture suppressed the responses to the same degree in both areas. These results might suggest that there are some differences in noxious-suppressive action between morphine and the endogenous opiates released by electroacupuncture stimulation.

摘要

研究了吗啡和电针对大鼠牙髓刺激后皮质诱发反应的影响。与初级体感区相比,吗啡对次级体感区这些反应的抑制作用更强,而电针在两个区域对反应的抑制程度相同。这些结果可能表明,吗啡与电针刺激释放的内源性阿片类物质在伤害性抑制作用方面存在一些差异。

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