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钙在四氧嘧啶糖尿病大鼠动脉和静脉平滑肌中的摄取与分布。

Ca2+ uptake and distribution in alloxan-diabetic rat arterial and venous smooth muscle.

作者信息

Turlapaty P D, Altura B T, Altura B M

出版信息

Experientia. 1980 Nov 15;36(11):1298-9. doi: 10.1007/BF01969599.

DOI:10.1007/BF01969599
PMID:7449917
Abstract

This report demonstrates that in experimental diabetes mellitus (DM) calcium uptake and its distribution is altered in rat aortic but not in portal venous smooth muscle. Results are interpreted as consequences of increased calcium binding by aortic smooth muscle in experimental DM, which could account for the hyporeactivity of alloxan diabetic rat aorta reported previously.

摘要

本报告表明,在实验性糖尿病(DM)中,大鼠主动脉平滑肌的钙摄取及其分布发生改变,但门静脉平滑肌未出现这种情况。这些结果被解释为实验性糖尿病中主动脉平滑肌钙结合增加的后果,这可能是先前报道的四氧嘧啶糖尿病大鼠主动脉反应性降低的原因。

相似文献

1
Ca2+ uptake and distribution in alloxan-diabetic rat arterial and venous smooth muscle.钙在四氧嘧啶糖尿病大鼠动脉和静脉平滑肌中的摄取与分布。
Experientia. 1980 Nov 15;36(11):1298-9. doi: 10.1007/BF01969599.
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引用本文的文献

1
The plasma-membrane component is the primary site of action of alloxan on ATP-driven Ca2+ transport in vascular-muscle microsomal fractions.在血管肌肉微粒体组分中,质膜成分是四氧嘧啶作用于ATP驱动的Ca2+转运的主要作用位点。
Biochem J. 1988 Aug 15;254(1):293-6. doi: 10.1042/bj2540293.
2
Mechanism of inhibition by alloxan of ATP-driven calcium transport by vascular smooth muscle microsomes.四氧嘧啶对血管平滑肌微粒体ATP驱动的钙转运的抑制机制。
J Bioenerg Biomembr. 1988 Aug;20(4):517-31. doi: 10.1007/BF00762207.

本文引用的文献

1
Vascular Smooth Muscle: Dual Effect of Calcium.血管平滑肌:钙的双重作用。
Science. 1963 Feb 15;139(3555):597-9. doi: 10.1126/science.139.3555.597.
2
Pentobarbital sodium inhibits calcium uptake in vascular smooth muscle.
Biochim Biophys Acta. 1980 Jan 25;595(2):309-12. doi: 10.1016/0005-2736(80)90093-0.
3
A quantitative study of peripheral arterial calcification and glucose tolerance in elderly diabetics and non-diabetics.
Diabetologia. 1971 Dec;7(6):409-13. doi: 10.1007/BF01212055.
4
Chemical studies on the arterial wall in relation to atherosclerosis.
Ann N Y Acad Sci. 1968 Nov 21;149(2):643-54. doi: 10.1111/j.1749-6632.1968.tb53824.x.
5
Barbiturates and aortic and venous smooth-muscle function.
Anesthesiology. 1975 Oct;43(4):432-44. doi: 10.1097/00000542-197510000-00009.
6
Calcium exchange in vascular smooth muscle, action of noradrenaline and lanthanum.血管平滑肌中的钙交换、去甲肾上腺素和镧的作用。
J Physiol. 1976 Aug;260(1):21-35. doi: 10.1113/jphysiol.1976.sp011501.
7
Extracellular magnesium ions control calcium exchange and content of vascular smooth muscle.
Eur J Pharmacol. 1978 Dec 1;52(3-4):421-3. doi: 10.1016/0014-2999(78)90303-5.
8
Interactions of Tris buffer and ethanol on agonist-induced responses of vascular smooth muscle and on calcium-45 uptake.Tris缓冲液与乙醇对血管平滑肌激动剂诱导反应及对45钙摄取的相互作用。
J Pharmacol Exp Ther. 1979 Oct;211(1):59-67.
9
Ethanol reduces Ca2+ concentrations in arterial and venous smooth muscle.
Experientia. 1979 May 15;35(5):639-40. doi: 10.1007/BF01960370.
10
Tris(hydroxymethyl)aminomethane inhibits calcium uptake in vascular smooth muscle.
Biochim Biophys Acta. 1979 Mar 8;551(2):459-62. doi: 10.1016/0005-2736(89)90021-7.