Hoefling K K, Schroeter A L
J Am Acad Dermatol. 1980 Sep;3(3):237-40. doi: 10.1016/s0190-9622(80)80184-8.
Direct immunofluorescence of scabies lesions revealed IgM, IgA, C3, and fibrin in the cornified layer of the epidermis, dermoepidermal junction, and papillary dermal vessels. The granular deposits of IgM and IgG in the dermoepidermal junction had a pattern similar to that found in lupus erythematosus. These findings support a humoral immune response secondary to scabetic infestation.
疥疮皮损的直接免疫荧光检查显示,在表皮角质层、真皮表皮交界处和乳头真皮血管中有IgM、IgA、C3和纤维蛋白。真皮表皮交界处IgM和IgG的颗粒状沉积物具有与红斑狼疮中发现的相似模式。这些发现支持疥疮感染继发的体液免疫反应。