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Influx of gamma-aminobutyric acid and alpha-aminoisobutyric acid into mouse cerebrum slices incubated in a pyruvate medium with or without added glucose or glucose analogues compared with influx from a glucose medium.

作者信息

Cohen S R

出版信息

J Neurochem. 1980 Oct;35(4):1008-12. doi: 10.1111/j.1471-4159.1980.tb07101.x.

DOI:10.1111/j.1471-4159.1980.tb07101.x
PMID:7452287
Abstract

Concentrative influx of gamma-aminobutyric acid (GABA) and alpha-amino-isobutyric acid (AIB) into incubated mouse cerebrum slices is decreased when pyruvate is substituted for glucose. Influx of GABA from pyruvate medium is not increased by presence of glucose, 2-deoxy-D-glucose (2-DOG), or 3-O-methyl-D-glucose (3-O-MeG). Influx of AIB is restored to the rate from glucose medium if 2-DOG is present initially, but is not restored if 2-DOG is added with AIB. Influx is not restored if 3-O-MeG is present initially, but is restored if 3-O-MeG is added with AIB. Influx is restored if glucose is present initially or is added with AIB.

摘要

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引用本文的文献

1
"Exchange diffusion": rate equations for the influx of alpha-aminoisobutyric acid into mouse cerebrum slices containing this amino acid.“交换扩散”：α-氨基异丁酸流入含有该氨基酸的小鼠大脑切片的速率方程。
J Bioenerg Biomembr. 1985 Oct;17(5):305-26. doi: 10.1007/BF00751107.