Awad A B
J Nutr. 1981 Jan;111(1):34-9. doi: 10.1093/jn/111.1.34.
Feeding rats diets rich in either safflower oil or coconut oil resulted in a significant change in the lipid composition of epididymal fat pads as compared with those obtained from rats fed a commercial stock diet. A safflower oil diet resulted in an increase in tissue cholesterol and a decrease in phospholipid concentration as compared with the stock diet. A coconut oil diet resulted in a decrease in both tissue cholesterol and phospholipid concentrations as compared with the stock diet. Adipose tissue fatty acid composition was also altered due to these dietary manipulations. Glucose utilization by adipose tissue from animals fed the safflower oil diet was 2 and 10 times greater than glucose utilization by adipose tissue from animals fed the stock and coconut oil diets, respectively. The coconut oil diet resulted in an increase in the percentage of glucose incorporated into adipose tissue diglycerides, free fatty acids and cholesterol esters and a decrease in the percentage of glucose incorporated into triglycerides as compared with animals fed the stock or safflower oil diet. The incorporation of glucose into adipose tissue fatty acids was depressed by a saturated fatty acid diet as compared with either a polyunsaturated fatty acid diet or the stock diet.
与喂食商业常规饲料的大鼠相比，给大鼠喂食富含红花油或椰子油的饲料会导致附睾脂肪垫的脂质组成发生显著变化。与常规饲料相比，红花油饲料会使组织胆固醇增加，磷脂浓度降低。与常规饲料相比，椰子油饲料会使组织胆固醇和磷脂浓度均降低。这些饮食操作也改变了脂肪组织的脂肪酸组成。喂食红花油饲料的动物的脂肪组织对葡萄糖的利用率分别是喂食常规饲料和椰子油饲料的动物的脂肪组织对葡萄糖利用率的2倍和10倍。与喂食常规饲料或红花油饲料的动物相比，椰子油饲料会使掺入脂肪组织甘油二酯、游离脂肪酸和胆固醇酯中的葡萄糖百分比增加，而掺入甘油三酯中的葡萄糖百分比降低。与多不饱和脂肪酸饲料或常规饲料相比，饱和脂肪酸饲料会抑制葡萄糖掺入脂肪组织脂肪酸。
