King D J, Griffiths K, Hall C E, Cooper N C, Morrison D J
J R Coll Gen Pract. 1980 Oct;30(219):614-8.
Barbiturate prescribing in general practice in Northern Ireland was monitored from computer data on prescription pricing for the years 1966 to 1979, and subjected to two methods of statistical analysis.Over the last decade a very marked decline in the prescribing of barbiturate hypnotics was accompanied by progressive decreases in barbiturate anti-epileptic and combination product utilization. During the 1975 to 1977 CURB campaign there was a statistically significant greater decrease in the total quantity of barbiturate hypnotics prescribed, but the downward trend in the numbers of prescriptions written was not significantly greater than before the campaign. The main effect of CURB, therefore, was to reduce the average quantity of barbiturate per prescription. The changes in barbiturate combination product prescribing between the CURB years were consistently large, whilst anti-epileptic barbiturate prescribing decreased less significantly towards the end of the campaign.
通过1966年至1979年处方定价的计算机数据对北爱尔兰全科医疗中巴比妥类药物的处方情况进行了监测,并采用了两种统计分析方法。在过去十年中,巴比妥类催眠药的处方量显著下降,同时巴比妥类抗癫痫药和复方制剂的使用量也在逐渐减少。在1975年至1977年的CURB运动期间,巴比妥类催眠药的处方总量在统计学上有显著更大幅度的下降,但所开具处方数量的下降趋势并不比运动前显著更大。因此,CURB的主要作用是减少每张处方中巴比妥类药物的平均用量。在CURB运动期间,巴比妥类复方制剂的处方变化一直很大,而抗癫痫巴比妥类药物的处方在运动接近尾声时减少得不太明显。