Cardinal D C, Higgs G A
J Pharmacol Methods. 1980 Sep;4(2):109-14. doi: 10.1016/0160-5402(80)90030-3.
A simple photometric device has been developed for measuring changes in blood vessel diameter in the microcirculation in conjunction with a monochrome television microscope. The device consists of a photocell mounted at the end of a small conical hood, which is attached to the screen of the television monitor. The photocell responds to changes in light emitted from the screen during dilatation or constriction of a blood vessel, and a continuous record of these changes is obtained by displaying the output from the photocell on a pen recorder. By using one or more photocells, mounted in separate hoods, the diameter of a number of vessels can be recorded simultaneously. The device has been used to record changes in the diameter of precapillary arterioles and postcapillary venules in the hamster cheek pouch microcirculation. The device has the advantage over image-shearing techniques of being automatic, and it is also considerably less expensive than a number of automated electro-optical or scanning systems.
已开发出一种简单的光度测量装置，用于结合单色电视显微镜测量微循环中血管直径的变化。该装置由安装在小锥形罩末端的光电管组成，该锥形罩连接到电视监视器的屏幕上。在血管扩张或收缩期间，光电管对屏幕发出的光的变化作出响应，并且通过在笔式记录仪上显示光电管的输出来获得这些变化的连续记录。通过使用安装在单独罩中的一个或多个光电管，可以同时记录多个血管的直径。该装置已用于记录仓鼠颊囊微循环中毛细血管前微动脉和毛细血管后微静脉直径的变化。与图像剪切技术相比，该装置具有自动的优点，并且它也比许多自动电光或扫描系统便宜得多。
