Oudart J L, Roffi J
Med Trop (Mars). 1978 Sep-Oct;38(5):565-73.
The prevalence of HBs Ag has been determined by counter-immuno-electrophoresis among 16,006 Africans of all ages and both sexes living in 132 villages chosen at random in whole Senegal. 8,83 +/- 0,5 p. 100 of the examined people were positive for HBs Ag. HBs Ag is much more frequent among males (11,1 p. 100) than females (7,0 p. 100). Almost non existent before the age of 1, prevalence increases during childhood and reaches its summit between 10 and 14 years for boys (14,7 p. 100) and between 20 and 24 for women (10,1 p. 100), then it decreases regularly with old age and become negligible over 60. Ethnic factors and way of living are more important than geographical factors. Subtyping demonstrated the importance of contamination inside families and consequently the preponderance of oral over percutaneous transmission.
在塞内加尔全国随机选取的132个村庄中,对16006名不同年龄和性别的非洲人进行了对流免疫电泳检测,以确定乙肝表面抗原(HBs Ag)的流行率。受检者中8.83±0.5%的人HBs Ag呈阳性。男性(11.1%)的HBs Ag阳性率远高于女性(7.0%)。1岁前几乎不存在,儿童期患病率上升,男孩在10至14岁达到高峰(14.7%),女性在20至24岁达到高峰(10.1%),然后随年龄增长而逐渐下降,60岁以上可忽略不计。种族因素和生活方式比地理因素更重要。亚型分析表明家庭内部感染的重要性,因此经口传播比经皮传播更为普遍。