[Influence of carbon disulfide on hemostasis in rabbits. I. Studies on coagulation and fibrinolysis].

Rabbits were exposed to carbon disulphide vapours in the toxicological chamber. Fibrinogen level, antiplasmin activity and soluble fibrin monomer complexes in the blood were increased, fibrinolysis time was prolonged. These disturbances in hemostasis depend on the concentration of carbon disulphide in the inhaled air and on the intoxication time. The authors suggest that these findings depend on the changed lipid metabolism and on the direct antagonistic influence of CS2 on coagulation and fibrynolysis agents.