Cwajda H, Woyke M
Med Pr. 1978;29(5):387-91.
Rabbits were exposed to carbon disulphide vapours in the toxicological chamber. Fibrinogen level, antiplasmin activity and soluble fibrin monomer complexes in the blood were increased, fibrinolysis time was prolonged. These disturbances in hemostasis depend on the concentration of carbon disulphide in the inhaled air and on the intoxication time. The authors suggest that these findings depend on the changed lipid metabolism and on the direct antagonistic influence of CS2 on coagulation and fibrynolysis agents.
将兔子置于毒理学实验舱中，使其暴露于二硫化碳蒸汽中。结果发现，兔子血液中的纤维蛋白原水平、抗纤溶酶活性和可溶性纤维蛋白单体复合物增加，纤维蛋白溶解时间延长。这些止血功能的紊乱取决于吸入空气中二硫化碳的浓度以及中毒时间。作者认为，这些发现取决于脂质代谢的改变以及二硫化碳对凝血和纤维蛋白溶解因子的直接拮抗作用。
