Castro-Vita H, Salazar O M, Scarantino C, Rubin P, De Cova M
Rev Interam Radiol. 1980 Jul;5(3):77-82.
"Analysis of 29 cases evaluated at SMG, Rochester, N.Y." This study analyzed 29 patients with the diagnosis of medulloblastoma evaluated at Strong Memorial Hospital, Rochester, New York. Twenty-three patients received combined (surgery and radiotherapy) treatment. Six had surgery alone. Chemotherapy was never employed as a primary treatment, however, two cases were treated with drugs at the time of relapse. The patients having craniospinal irradiation had a better survival rate when compared with the group receiving cranial irradiation or surgery alone. The five year survival rate for the first group was 50% versus 20% for the second group and 0% for the third group. The main cause of failure was recurrence in the posterior fossa. Fifteen patients failed in this area representing 88% of the total failures. Seeding to the spinal cord was determined in 5 patients, four of whom did not have spinal cord irradiation. One patient failed outside the field of treatment in the conus medullaris six months after radiation.
“对纽约罗切斯特市斯特朗纪念医院评估的29例患者的分析” 本研究分析了在纽约罗切斯特市斯特朗纪念医院确诊为髓母细胞瘤的29例患者。23例患者接受了联合（手术和放疗）治疗。6例仅接受了手术。化疗从未作为主要治疗方法，然而，有2例在复发时接受了药物治疗。与仅接受颅脑照射或手术的组相比，接受全脑全脊髓照射的患者生存率更高。第一组的五年生存率为50%，第二组为20%，第三组为0%。失败的主要原因是后颅窝复发。15例患者在该区域失败，占总失败病例的88%。5例患者发生脊髓播散，其中4例未接受脊髓照射。1例患者在放疗6个月后在治疗野以外的脊髓圆锥部位出现失败。
