髓母细胞瘤

Medulloblastomas.

作者信息

Gökalp H Z, Arasil E, Kanpolat Y, Erdogan A, Deda H, Unlü A

机构信息

Ankara University Faculty of Medicine, Department of Neurosurgery, Turkey.

出版信息

Neurochirurgia (Stuttg). 1993 May;36(3):87-9. doi: 10.1055/s-2008-1053802.

DOI:10.1055/s-2008-1053802

PMID:8321384

Abstract

81 patients with biopsy proven medulloblastoma with a mean age of 11.4 years were reviewed. Total removal of the tumour was accomplished in 18 cases (22.2%), subtotal removal in 55 cases (67.9%) and biopsy alone in 8 cases (9.9%). 34 patients (27.5%) had a recurrence of the tumour and 8 patients underwent a second posterior fossa exploration at the time of recurrence. In patients with total resection, five-year survival was 27.7%. With partial resection, five-year survival decreased to 14.5%. In patients with radiotherapy chemotherapy, 21.4% survived 5 years after treatment but this rate decreased to 18.4% in patients treated with radiotherapy only. The surgical mortality rate was 12.3%.

摘要

回顾了81例经活检证实为髓母细胞瘤的患者，平均年龄11.4岁。18例（22.2%）实现了肿瘤全切，55例（67.9%）次全切除，8例（9.9%）仅行活检。34例（27.5%）肿瘤复发，8例复发时接受了二次后颅窝探查。全切患者的五年生存率为27.7%。部分切除患者的五年生存率降至14.5%。接受放化疗的患者，治疗后5年生存率为21.4%，但仅接受放疗的患者这一比例降至18.4%。手术死亡率为12.3%。