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[真核染色体的三级结构组织]

[Three levels of structural organization of the eukaryotic chromosomes].

作者信息

Georgiev G P, Bakaev V V

出版信息

Mol Biol (Mosk). 1978 Nov-Dec;12(6):1205-30.

PMID:745600
Abstract

Three levels of structural organization of eukaryotic DNA in the cell nucleus are considered in this paper: (i) the chain of nucleosomes; (ii) the solenoidal or superbead (nucleomere) model of compactization of the nucleosomal fiber; (iii) the mode of suprasolenoidal DNP-packing--loops or domains. Recent results bearing on the relation of these three levels to functional activity of chromatin are also discussed.

摘要

本文探讨了真核细胞细胞核中DNA的三个结构组织层次:(i)核小体链;(ii)核小体纤维压缩的螺线管或超珠(核粒)模型;(iii)超螺线管DNP堆积模式——环或结构域。还讨论了与染色质功能活性相关的这三个层次关系的最新研究结果。

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