再生大鼠肾上腺孵育物中19-羟脱氧皮质酮的鉴定。
Identification of 19-hydroxydeoxycorticosterone in regenerating rat adrenal incubations.
作者信息
Dale S L, Holbrook M M, Melby J C
出版信息
Steroids. 1980 Nov;36(5):601-9. doi: 10.1016/0039-128x(80)90082-3.
PMID:7456103
Abstract
19-Hydroxydeoxycorticosterone (19-OH-DOC) was isolated from the incubation medium of enucleated rat adrenal glands during the early sodium retaining phase. Identification included comparison of chromatographic mobility of parent and derivatized compound with standard prepared by the 21-hydroxylation of 19-hydroxyprogesterone and mass spectrometry. The possible role of 19-OH-DOC as a precursor is discussed.
摘要
在早期钠潴留阶段，从摘除肾上腺的大鼠肾上腺孵育介质中分离出了19-羟基脱氧皮质酮（19-OH-DOC）。鉴定过程包括将母体化合物和衍生化化合物的色谱迁移率与通过19-羟基孕酮的21-羟化反应制备的标准品进行比较，以及质谱分析。本文讨论了19-OH-DOC作为前体的可能作用。
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引用本文的文献
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