Andrianova L F, Beregi E, Butenko G M, Echneva T L
Z Alternsforsch. 1980;35(2):165-70.
The effect of Levamisol, potassium polyadenylate, complete Freund's adjuvant and "antigen premunition" on the primary and secondary immunological response to sheep erythrocytes as well as the reaction of "graft versus host" were tested on mice of the CBA strain belonging to various age groups. The greatest stimulation effect in both types of response, i.e. humoral and cellular, was produced by "premunition". Levasimole clearly increased the reaction of "graft versus host", while the humoral response was weakened. The application of potassium polyadenylate produced a weaker stimulus to the response to sheep erythrocytes, and it was not effective in the response of "graft versus host". The complete Freund's adjuvant had no influence whatsover on the humoral immune response in old mice.
在不同年龄组的CBA品系小鼠身上，测试了左旋咪唑、聚腺苷酸钾、完全弗氏佐剂和“抗原预免疫”对绵羊红细胞初次和二次免疫反应以及“移植物抗宿主”反应的影响。“预免疫”在体液和细胞这两种免疫反应类型中均产生了最大的刺激作用。左旋咪唑明显增强了“移植物抗宿主”反应，同时削弱了体液免疫反应。聚腺苷酸钾对绵羊红细胞反应的刺激作用较弱，并且在“移植物抗宿主”反应中无效。完全弗氏佐剂对老年小鼠的体液免疫反应没有任何影响。
