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[有无血液透析的肾功能不全的免疫学发现。II. 慢性血液透析条件下的K细胞活性]

[Immunological findings in kidney insufficiency with and without hemodialysis. II. K cell activity under chronic hemodialysis conditions].

作者信息

Varga A, Stosiek P, Lincke H U

出版信息

Z Urol Nephrol. 1980 May;73(5):367-71.

PMID:7456804
Abstract

In a group of patients with renal insufficiency in the chronic dialysis programme the K-cell-activity (antibody-depending cellular cytotoxicity) by means of 51-Cr-labelled chicken erythrocytes as target cells was determined and was found significantly decreased. The findings may be regarded as a sequel of the dialysis together with the already described T-lymphopenia. The reasons of this complex disturbance of the cellular immunity under conditions of dialysis are unknown.

摘要

在一组慢性透析项目中的肾功能不全患者中,以51铬标记的鸡红细胞作为靶细胞,测定了K细胞活性(抗体依赖性细胞毒性),发现其显著降低。这些发现可被视为透析的后果以及已描述的T淋巴细胞减少症。在透析情况下这种细胞免疫复杂紊乱的原因尚不清楚。

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