[Lessening the impairment of wound healing by pre-or postoperative quantitative factor-XIII substitution (author's transl)].

In the light of listed references, a report is given on the influence of the clotting factor XIII in experiments with animals as well as with patients. Through own examinations in 95 patients with severe abdominal and vessel surgery, a clear lessening of impairment of wound healing could be achieved by the quantitative pre- and postoperative substitution of the fibrin stabilizing factor.