下肢静脉溃疡患者血液中的凝血因子 XIII 缺乏症。
Factor XIII-deficiency in the blood of venous leg ulcer patients.
作者信息
Vanscheidt W, Hasler K, Wokalek H, Niedner R, Schöpf E
机构信息
Department of Dermatology, University of Freiburg, FRG.
出版信息
Acta Derm Venereol. 1991;71(1):55-7.
PMID:1676216
Abstract
Pericapillary fibrin cuffs are probably involved in the pathogenesis of venous leg ulcers. Factor XIII (Fibrin stabilizing factor) is of importance in wound healing. Its activity, which may affect ulceration, was found to be significantly reduced in the blood of venous leg ulcer patients and in post-phlebitic patients, compared with healthy controls.
摘要
毛细血管周围纤维蛋白袖套可能参与了下肢静脉溃疡的发病机制。因子 XIII（纤维蛋白稳定因子）在伤口愈合中起重要作用。与健康对照组相比，发现下肢静脉溃疡患者和静脉炎后患者血液中其活性显著降低，而这种活性可能会影响溃疡形成。
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