Lauckner W, Retzke U, Schwarz R
Zentralbl Gynakol. 1980;102(16):927-31.
Intravenous injection of 2.5 mg of droperidol and 0,05 mg of fentanyl to ten women with clinically intact cardiovascular system in advanced pregnancy and the cardiovascular effects of such injection were studied by means of quantitative sphygmometry. - Mean arterial blood pressure was found to drop slightly but with significance, while the blood pressure amplitude went up. Heart rates remained largely constant. Significant increase in cardiac output, consequently, resulted solely from increase in stroke volume. Total peripheral resistance was reduced with significance. Medication, using the above combination of drugs, may be recommended for obstetric analgesisa, because of its favourable impact in terms of hemodynamics.
对10名心血管系统临床功能正常的晚期妊娠妇女静脉注射2.5毫克氟哌利多和0.05毫克芬太尼,并通过定量血压测量法研究这种注射的心血管效应。结果发现平均动脉血压略有下降但具有显著性,而血压幅度上升。心率基本保持不变。因此,心输出量的显著增加完全是由于每搏输出量的增加。总外周阻力显著降低。由于上述药物组合在血流动力学方面具有有利影响,因此可推荐用于产科镇痛。