Varga L, Fodor E, Sasvári M, Lonovics J, Varró V
Acta Med Acad Sci Hung. 1980;37(1):121-5.
BOC-14C-glycine pentapeptide undergoes hydrolysis on incubation with tissue homogenates. The enzyme activities responsible for hydrolysis have the pancreas, lung and small intestine as their sites. No enzyme activity is demonstrable in liver, kidney and muscle. While intrapulmonary enzyme activity is marked by thermolability, the activities of the pancreatic and intestinal tissues are scarcely affected by heat. The optimum pH is 7.1 for the pulmonary, 7.1 and 10 for the pancreatic and small intestinal enzyme activity. EDTA has proved inhibitory to the enzyme activities of all three organs, in contrast to Gordox and to soybean trypsin inhibitor which leave these activities unaltered.
BOC - 14C - 甘氨酸五肽与组织匀浆一起温育时会发生水解。负责水解的酶活性部位在胰腺、肺和小肠。在肝脏、肾脏和肌肉中未检测到酶活性。肺内酶活性具有热不稳定性，而胰腺和肠道组织的活性几乎不受热的影响。肺酶活性的最适pH为7.1，胰腺和小肠酶活性的最适pH分别为7.1和10。与戈多克斯和大豆胰蛋白酶抑制剂不同，EDTA已被证明对所有三个器官的酶活性均有抑制作用，后两者不会改变这些活性。
