Stewart I, Peel S
Anat Embryol (Berl). 1980;160(2):227-38. doi: 10.1007/BF00301863.
A study has been made of the distribution of, and synthesis of DNA by, granulated metrial gland cells at implantation sites in the pregnant mouse uterus. Granulated cells were found in small numbers randomly distributed throughout the endometrium on day 4 1/2 of pregnancy. Subsequently cells of this type were lost from the antimesometrial and lateral decidua but increased dramatically in number in the developing decidua basalis. From day 7 1/2 granulated cells populated the mesometrial triangle to form the metrial gland. A high proportion of granulated cells was found to incorporate tritiated thymidine and the distribution of such cells is described. However, no granulated cells were found to incorporate tritiated thymidine at or after day 12 of pregnancy. In addition the loss of granulated metrial gland cells from the implantation site is described and is accounted for by degeneration in situ and also by migration via vascular channels. It is suggested that this latter route could be of functional significance.
对妊娠小鼠子宫着床部位颗粒状子宫内膜腺细胞的分布及DNA合成进行了研究。在妊娠4.5天时，发现颗粒状细胞数量较少，随机分布于整个子宫内膜。随后，这种类型的细胞从子宫系膜对侧和侧蜕膜中消失，但在发育中的基蜕膜中数量急剧增加。从7.5天开始，颗粒状细胞填充子宫系膜三角区，形成子宫内膜腺。发现高比例的颗粒状细胞掺入了氚标记的胸腺嘧啶核苷，并描述了此类细胞的分布情况。然而，在妊娠12天及之后，未发现颗粒状细胞掺入氚标记的胸腺嘧啶核苷。此外，还描述了颗粒状子宫内膜腺细胞从着床部位的消失情况，这是由原位退化以及通过血管通道迁移所致。有人认为后一种途径可能具有功能意义。
