Dalal J J, Dart A M, Davies H A, Sheridan D J, Ruttley M S, Henderson A H
Br Heart J. 1981 Feb;45(2):181-5. doi: 10.1136/hrt.45.2.181.
Vascular responses to ergometrine were compared in groups of patients subject to coronary artery spasm, or oesophageal spasm, or neither. We measured the degree of diffuse narrowing at different coronary artery sites (not in spasm), and the rise in blood pressure. The data provide no evidence for a generalised sensitivity to alpha-adrenergic stimulation underlying either of these two clinical entities. The left main stem was narrowed significantly less than the three main branches of the coronary artery tree. The degree of diffuse coronary artery narrowing was not influenced by the presence or absence of minor (less than or equal to 50%) fixed stenotic lesions, nor by the initial calibre of the arteries. Ergometrine did not alter arterial lactate concentration or lactate extraction in the absence of coronary spasm.
对患有冠状动脉痉挛、食管痉挛或两者皆无的患者组进行了麦角新碱的血管反应比较。我们测量了不同冠状动脉部位（非痉挛部位）的弥漫性狭窄程度以及血压升高情况。数据未提供证据表明这两种临床病症存在对α-肾上腺素能刺激的普遍敏感性。左主干的狭窄程度明显低于冠状动脉树的三个主要分支。弥漫性冠状动脉狭窄程度不受轻度（小于或等于50%）固定狭窄病变的有无影响，也不受动脉初始管径的影响。在无冠状动脉痉挛的情况下，麦角新碱不会改变动脉乳酸浓度或乳酸摄取。
