Soybean trypsin inhibitor (Kunitz) and its complex with trypsin. Carbon-13 nuclear magnetic resonance studies of the reactive site arginine.

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作者信息

Baillargeon M W, Laskowski M, Neves D E, Porubcan M A, Santini R E, Markely J L

出版信息

Biochemistry. 1980 Dec 9;19(25):5703. doi: 10.1021/bi00566a006.

DOI:10.1021/bi00566a006

PMID:7459339

Abstract

摘要

相似文献

Soybean trypsin inhibitor (Kunitz) and its complex with trypsin. Carbon-13 nuclear magnetic resonance studies of the reactive site arginine.

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13C NMR studies of the binding of soybean trypsin inhibitor to trypsin.

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Replacement of lysine by arginine, phenylalanine and tryptophan in the reactive site of the bovine trypsin-kallikrein inhibitor (Kunitz) and change of the inhibitory properties.牛胰蛋白酶-激肽释放酶抑制剂（Kunitz）活性位点中赖氨酸被精氨酸、苯丙氨酸和色氨酸取代及其抑制特性的改变。

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Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, VII. Determination of the amino-acid sequence of the trypsin-released inhibitor from bovine inter-alpha-trypsin inhibitor.

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Preparation and characterization of the active derivative bovine trypsin-kallikrein inhibitor (Kunitz) with the reactive site lysine-15 -- alanine-16 hydrolyzed.活性位点赖氨酸-15 -- 丙氨酸-16水解的活性衍生物牛胰蛋白酶-激肽释放酶抑制剂（Kunitz）的制备与表征

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Assignment of the histidine proton magnetic resonance peaks of soybean trypsin inhibitor (Kunitz) by a differertial deuterium exchange technique.用差分氘交换技术对大豆胰蛋白酶抑制剂（Kunitz）的组氨酸质子磁共振峰进行归属

Biochemistry. 1975 Jul 15;14(14):3234-7. doi: 10.1021/bi00685a032.

Chemical-enzymatic insertion of an amino acid residue in the reactive site of soybean trypsin inhibitor (Kunitz).在大豆胰蛋白酶抑制剂（Kunitz）的活性位点进行氨基酸残基的化学酶促插入。

Biochemistry. 1976 Mar 23;15(6):1309-15. doi: 10.1021/bi00651a022.

Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, I. Determination of the amino acid sequence of the antitryptic domain by solid-phase Edman degradation.通过对α-胰蛋白酶抑制剂进行有限蛋白酶解得到的库尼茨型蛋白酶抑制剂，I. 用固相埃德曼降解法测定抗胰蛋白酶结构域的氨基酸序列。

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Interaction of the Kunitz soybean trypsin inhibitor with bovine trypsin. Evidence for an an acy-enzyme intermediate during complexation.库尼茨大豆胰蛋白酶抑制剂与牛胰蛋白酶的相互作用。络合过程中酰基酶中间体的证据。

Biochemistry. 1977 May 31;16(11):2474-8. doi: 10.1021/bi00630a024.

Kunitz-type proteinase inhibitors derived by limited proteolysis of the inter-alpha-trypsin inhibitor, X. The amino-acid sequences of the trypsin-released inhibitors from horse and pig inter-alpha-trypsin inhibitors.通过对α-胰蛋白酶抑制剂进行有限蛋白酶解衍生得到的Kunitz型蛋白酶抑制剂X。来自马和猪α-胰蛋白酶抑制剂的胰蛋白酶释放抑制剂的氨基酸序列。

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