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血清精子凝集抗体在不育男性婚姻中的意义。

The significance of serum sperm-agglutinating antibodies in men with infertile marriages.

作者信息

Hargreave T B, Haxton M, Whitelaw J, Elton R, Chisholm G D

出版信息

Br J Urol. 1980 Dec;52(6):566-70. doi: 10.1111/j.1464-410x.1980.tb03116.x.

DOI:10.1111/j.1464-410x.1980.tb03116.x
PMID:7459591
Abstract

Three hundred consecutive male partners of infertile marriages had serum samples tested for sperm agglutinating and sperm immobilising antibodies, using a micro-technique: 30.3% were found to be positive. Out of a control group of 100 fertile men 10 had antibodies detected (10%) and these at low titre; this difference was significant. The results of these serum tests were found to correlate with the results of seminal plasma tests, the mixed antiglobulin reaction for IgG and sperm cervical mucus contact testing, although all of these tests were less discriminatory with regard to fertility. The serum micro-immobilisation test showed a statistical association with fertility when analysed in those couples where both husband's and wife's tests showed no other bar to fertility.

摘要

对300名不育婚姻中连续的男性伴侣的血清样本,采用微量技术检测精子凝集抗体和精子制动抗体:发现30.3%呈阳性。在100名生育能力正常男性的对照组中,10人检测到抗体(10%),且抗体滴度较低;这种差异具有统计学意义。这些血清检测结果与精浆检测结果、IgG混合抗球蛋白反应以及精子与宫颈黏液接触试验结果相关,尽管所有这些检测在生育能力方面的鉴别力较低。在夫妻双方检测均未显示其他生育障碍的夫妇中进行分析时,血清微量制动试验显示与生育能力存在统计学关联。

相似文献

1
The significance of serum sperm-agglutinating antibodies in men with infertile marriages.血清精子凝集抗体在不育男性婚姻中的意义。
Br J Urol. 1980 Dec;52(6):566-70. doi: 10.1111/j.1464-410x.1980.tb03116.x.
2
Detection of autoimmunity to sperm: mixed antiglobulin reaction (MAR) test or sperm agglutination? A study on 537 men from infertile couples.精子自身免疫的检测:混合抗球蛋白反应(MAR)试验还是精子凝集试验?一项针对537对不育夫妇男性的研究。
Fertil Steril. 1986 Jul;46(1):86-91. doi: 10.1016/s0015-0282(16)49463-x.
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The incidence and influence of antisperm antibodies in infertile human couples on sperm-cervical mucus interactions and subsequent fertility.不育夫妇中抗精子抗体对精子 - 宫颈黏液相互作用及后续生育能力的发生率和影响。
Fertil Steril. 1982 Oct;38(4):439-46. doi: 10.1016/s0015-0282(16)46578-7.
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Interrelationships among semen characteristics, antisperm antibodies, and cervical mucus penetration assays in infertile human couples.不育夫妇精液特征、抗精子抗体与宫颈黏液穿透试验之间的相互关系。
Fertil Steril. 1989 Mar;51(3):486-92. doi: 10.1016/s0015-0282(16)60559-9.
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Relationship between the direct mixed antiglobulin reaction (MAR) test and spontaneous sperm agglutination in men from infertile couples.
J Med Assoc Thai. 1995 Feb;78(2):89-93.
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Sperm-agglutinating antibodies in infertile couples.不育夫妇体内的精子凝集抗体。
Arch Androl. 1979 May;2(3):241-5. doi: 10.3109/01485017908987319.
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Correlation between the direct IgG MAR test (mixed antiglobulin reaction test) and seminal analysis in men from infertile couples.不育夫妇男性中直接IgG MAR试验(混合抗球蛋白反应试验)与精液分析之间的相关性。
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Lancet. 1977 Jun 11;1(8024):1228-30. doi: 10.1016/s0140-6736(77)92437-0.

引用本文的文献

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UNDERSTANDING MALE FACTOR IN INFERTILITY.了解男性因素导致的不育症。
Med J Armed Forces India. 1999 Jul;55(3):181-182. doi: 10.1016/S0377-1237(17)30435-5. Epub 2017 Jun 26.
2
Can semen analysis predict the presence of antisperm antibodies in patients with primary infertility?精液分析能否预测原发性不孕患者抗精子抗体的存在?
World J Urol. 1995;13(5):318-22. doi: 10.1007/BF00185976.