Menge A C, Medley N E, Mangione C M, Dietrich J W
Fertil Steril. 1982 Oct;38(4):439-46. doi: 10.1016/s0015-0282(16)46578-7.
Analysis of serum samples from 698 infertile couples revealed antisperm antibodies present in 16.5% of the men and 21.6% of the women. Overall, 31.1% of the couples possessed at least one individual with positive results. Sperm-immobilized activity was detected in 29.6% of the cervical mucus (CM) samples from 459 women. Reduced sperm penetration of CM was significantly associated with serum titers of antisperm antibodies in both sexes and also with immobilizing activity in CM of women. The incidence of subsequent pregnancy in 376 infertile couples was reduced significantly if one or both partners had antisperm antibodies in serum or in genital tract secretions. The latter was reflected by evaluation of the immobilization, penetration, and shaking phenomenon of sperm in CM.
对698对不孕夫妇的血清样本分析显示，16.5%的男性和21.6%的女性存在抗精子抗体。总体而言，31.1%的夫妇中至少有一方检测结果呈阳性。在459名女性的29.6%的宫颈黏液（CM）样本中检测到精子固定活性。CM中精子穿透能力降低与男女双方血清抗精子抗体滴度均显著相关，也与女性CM中的固定活性相关。如果一方或双方伴侣血清或生殖道分泌物中存在抗精子抗体，376对不孕夫妇随后怀孕的几率会显著降低。后者通过评估CM中精子的固定、穿透和摇晃现象得以体现。
