Hinton C P, Hughes R G
Br J Surg. 1981 Jan;68(1):45-6. doi: 10.1002/bjs.1800680115.
We have made a retrospective study of 197 patients who underwent 367 breast cyst aspirations and in whom the fluid obtained was sent for cytological examination between January 1974 and August 1976. Four specimens were reported as showing malignant cells in the aspirate. All of these were excised and 3 were confirmed to be malignant. A further 8 showed bizarre or atypical appearances, of which four were excised and 1 was malignant. The other 4 were subjected to repeat aspiration, at which time typical benign appearances were reported and no further action taken. No tumour developed in the follow-up period of at least 2 years. Of the patients whose initial cytology was benign, 51 were subjected to repeated aspiration of clinically recurrent cysts, 28 on 3 or more occasions. Ten patients underwent excision biopsy of histologically benign lesions. None of these 51 patients developed a malignant tumour at the site of the cyst in the 2-year follow-up period.
我们对197例患者进行了回顾性研究，这些患者在1974年1月至1976年8月期间接受了367次乳腺囊肿穿刺抽吸术，所获得的液体被送去做细胞学检查。有4份标本报告显示穿刺液中有恶性细胞。所有这些都被切除，其中3例被证实为恶性。另有8例显示出怪异或非典型外观，其中4例被切除，1例为恶性。另外4例进行了重复穿刺，此时报告为典型的良性外观，未采取进一步措施。在至少2年的随访期内未发生肿瘤。对于初始细胞学检查为良性的患者，51例因临床复发性囊肿接受了重复穿刺，其中28例进行了3次或更多次穿刺。10例患者对组织学上为良性的病变进行了切除活检。在这51例患者中，没有1例在2年随访期内在囊肿部位发生恶性肿瘤。
