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Liver-cell tumours in rats fed hexachlorobenzene.

作者信息

Smith A G, Cabral J R

出版信息

Cancer Lett. 1980 Dec;11(2):169-72. doi: 10.1016/0304-3835(80)90108-1.

DOI:10.1016/0304-3835(80)90108-1
PMID:7459845
Abstract

All animals in a group of female Agus rats fed 100 ppm of hexachlorobenzene (HCB) in their diet for up to 90 weeks developed multiple liver-cell tumours whereas none were seen in control rats. There was no evidence of skin lesions or nervous symptoms usually seen with higher doses of HCB. A high incidence of liver-cell tumours was also seen with MRC Wistar female rats fed HCB for 75 weeks.

摘要

相似文献

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Liver-cell tumours in rats fed hexachlorobenzene.
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The role of the immune system in hexachlorobenzene-induced toxicity.免疫系统在六氯苯诱导的毒性中的作用。
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2
Contamination of native fish stock by hexachlorobenzene and polychlorinated biphenyl residues.
Bull Environ Contam Toxicol. 1982 May;28(5):599-604. doi: 10.1007/BF01605591.
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A carcinogenic potency database of the standardized results of animal bioassays.一个关于动物生物测定标准化结果的致癌效力数据库。
Environ Health Perspect. 1984 Dec;58:9-319. doi: 10.1289/ehp.84589.
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Tumor promotion in the liver.肝脏中的肿瘤促进作用。
Arch Toxicol. 1985 Aug;57(3):147-58. doi: 10.1007/BF00290879.
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Porphyrias, porphyrins and hepatocellular cancer.卟啉病、卟啉与肝细胞癌
Br J Cancer. 1986 Jul;54(1):115-7. doi: 10.1038/bjc.1986.159.
6
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7
Biochemical, morphological and flow-cytometric evaluation of the effects of hexachlorobenzene on rat liver.六氯苯对大鼠肝脏影响的生化、形态学及流式细胞术评估
Cell Biol Toxicol. 1990 Apr;6(2):185-203. doi: 10.1007/BF00249593.