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[索尔达多病毒生态学:在媒介蜱类海滨钝缘蜱(奥氏钝缘蜱属)的组织中明显缺乏病毒抑制剂,韦尔梅尔和马尔盖,1967年]

[Ecology of Soldado virus: apparent lack of a viral inhibitor in th tissues of the vector tick Ornithodoros (Alectorobius) maritimus Vermeil and Marguet 1967].

作者信息

Chastel C, Roguès G

出版信息

Bull Soc Pathol Exot Filiales. 1980 Jul-Aug;73(4):399-404.

PMID:7460129
Abstract

It was previously postulated by others that suspensions of ticks O. (A.) maritmus may contain virucidal material (viral inhibitor) for Soldado virus leading to observe different infection rates according as the ticks were tested individually or in pools. In order to test this hypothesis, suspensions of nymphs of this species originating from a laboratory breeding stock, were mixed with Soldado virus before inoculation to suckling mice. No difference in mortality was observed between the mice receiving the virus exposed to tick suspensions and the controls. So, it seems unlike a viral inhibitor was responsible for the phenomenon. Other factors involved in Soldado virus ecology and possibly influencing the virus isolation efficiency are briefly discussed.

摘要

此前其他人曾推测,海滨钝缘蜱(O. (A.) maritmus)的悬液可能含有针对索尔达多病毒的杀病毒物质(病毒抑制剂),导致根据蜱虫是单独测试还是成组测试而观察到不同的感染率。为了验证这一假设,将源自实验室繁殖种群的该物种若虫悬液在接种给乳鼠之前与索尔达多病毒混合。接受暴露于蜱虫悬液的病毒的小鼠与对照组之间未观察到死亡率差异。因此,似乎不太可能是病毒抑制剂导致了这一现象。本文简要讨论了索尔达多病毒生态学中可能影响病毒分离效率的其他因素。

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