Floyd J L, Weiland F L, Hale A S, Nusynowitz M L
Clin Nucl Med. 1981 Feb;6(2):53-6. doi: 10.1097/00003072-198102000-00001.
A prospective investigation comparing Tc-99m-PIPIDA with Tc-99m-sulfur colloid in the detection of defects of the liver was carried out in 30 volunteers. By acquiring images of 1 million counts from 5-10 minutes postinjection, high quality hepatic images could be obtained with PIPIDA. Separate interpretations by three nuclear physicians yielded similar results between paired PIPIDA and sulfur colloid studies (KAV = 0.95 +/- .09, P less than 0.001). Early multiview imaging of the liver in the course of hepatobiliary evaluation with PIPIDA may yield valuable information relative to the presence of lesions.
在30名志愿者中进行了一项前瞻性研究，比较了锝-99m-吡哆醛异烟酰腙（Tc-99m-PIPIDA）与锝-99m-硫胶体在检测肝脏缺损方面的效果。通过在注射后5至10分钟采集100万计数的图像，使用PIPIDA可获得高质量的肝脏图像。三位核医学医师的独立解读显示，配对的PIPIDA和硫胶体研究结果相似（卡方值 = 0.95 ± 0.09，P < 0.001）。在使用PIPIDA进行肝胆评估过程中对肝脏进行早期多视角成像，可能会提供有关病变存在的有价值信息。
