Lowenfels A B
Gut. 1980 Dec;21(12):1090-2. doi: 10.1136/gut.21.12.1090.
For both males and females the age-standardised prevalence of asymptomatic gallstones found at necropsy in 15 countries correlated strongly with age-standardised mortality from cancers of the uterus, large bowel, and stomach. When deaths from cholecystitis were used as another measure of the frequency of gallstones similar positive correlations were observed across 28 countries. The results suggest that cholelithiasis and several common cancers share similar epidemiological and perhaps metabolic factors.
在15个国家中,尸检发现的无症状胆结石的年龄标准化患病率,无论对男性还是女性而言,都与子宫癌、大肠癌和胃癌的年龄标准化死亡率密切相关。当把胆囊炎导致的死亡作为胆结石发病率的另一衡量指标时,在28个国家中也观察到了类似的正相关关系。结果表明,胆石症和几种常见癌症具有相似的流行病学因素,或许还有代谢因素。