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肌萎缩侧索硬化症:日本尸检病例的全身并发症研究

Amyotrophic lateral sclerosis: a study of systemic complications in autopsy cases in Japan.

作者信息

Yabuki S, Ikeda H

出版信息

Folia Psychiatr Neurol Jpn. 1980;34(2):127-33. doi: 10.1111/j.1440-1819.1980.tb01521.x.

DOI:10.1111/j.1440-1819.1980.tb01521.x
PMID:7461510
Abstract

In a retrospective study involving 277 autopsy cases of amyotrophic lateral sclerosis (ALS) which had been published in the Annual of the Pathological Autopsy Cases in Japan, an investigation was made of concurrent visceral lesions. The results indicated that complications involving the digestive organs, urinary tract and supportive connective tissues were less frequent in ALS than in patients with degenerative diseases of the central nervous system who served as controls. Since a similar discrepancy was observed between patients with ALS and with encephalitis, it was postulated that the difference in incidences might not be simply explained by differences in patients' ages and the duration of illness.

摘要

在一项涉及277例肌萎缩侧索硬化症(ALS)尸检病例的回顾性研究中(这些病例已发表于《日本病理解剖病例年报》),对并发的内脏病变进行了调查。结果表明,与作为对照的中枢神经系统退行性疾病患者相比,ALS患者涉及消化器官、泌尿道和支持性结缔组织的并发症较少。由于在ALS患者和脑炎患者之间也观察到了类似的差异,因此推测发病率的差异可能不能简单地用患者年龄和病程的差异来解释。

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