Schindler A E, Duderstadt J
Fortschr Med. 1980 Sep 25;98(36):1374-8.
This study includes 389 cases of ectopic pregnancies and 34 cases with repeat ectopic pregnancies occurring from 1955 to 1974 at the University Women's Hospital Tuebingen. The incidence of ectopic pregnancy in relation to the number of births was 0.9%. The incidence of repeat ectopic pregnancy was 9.3%. The percentage of ectopic pregnancies was lower after 1966, but the percentage of repeat ectopic pregnancies remained unchanged. The menstrual history was non-revealing and 76.5% of the patients with repeat ectopic pregnancy had been pregnant prior to the first ectopic pregnancy. The average age at the time of the first ectopic pregnancy was 28.2 years and at the time of the second ectopic pregnancy 32.2 years. On the average, repeat ectopic pregnancy occurred 43.8 months later (range 6-192 months). In 2 repeat ectopic pregnancies a conservative management of the tube at the time of the first tubal pregnancy had been used. 61.5% of the first ectopic pregnancies and 62.5% of the repeat ectopic pregnancies were located in the ampullary portion of the tube, 38.5% respectively 34.4% in the isthmic portion and 0% respectively 3.1% in the intramural part. Among the 34 cases with repeat ectopic pregnancies 6 women had intrauterine pregnancies after the first ectopic pregnancy, but only 2 delivered live-born infants. The mortality for all ectopic pregnancies was 0%.
本研究纳入了1955年至1974年期间在图宾根大学妇女医院发生的389例异位妊娠病例以及34例重复异位妊娠病例。异位妊娠发生率与分娩数之比为0.9%。重复异位妊娠发生率为9.3%。1966年后异位妊娠的百分比有所降低，但重复异位妊娠的百分比保持不变。月经史无异常，76.5%的重复异位妊娠患者在首次异位妊娠前已怀孕。首次异位妊娠时的平均年龄为28.2岁，第二次异位妊娠时为32.2岁。平均而言，重复异位妊娠发生在首次异位妊娠43.8个月后（范围为6 - 192个月）。在2例重复异位妊娠中，首次输卵管妊娠时对输卵管采用了保守治疗。61.5%的首次异位妊娠和62.5%的重复异位妊娠位于输卵管壶腹部，分别有38.5%和34.4%位于峡部，分别有0%和3.1%位于子宫壁内部分。在34例重复异位妊娠病例中，6名女性在首次异位妊娠后有宫内妊娠，但只有2名分娩了活婴。所有异位妊娠的死亡率为0%。
