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通过内镜逆行胰胆管造影术和胰腺细胞学检查诊断胰腺癌。

Diagnosis of pancreatic carcinoma by means of endoscopic retrograde pancreatography and pancreatic cytology.

作者信息

Klapdor R, Soehendra N, Klöppel G, Steiner D

出版信息

Hepatogastroenterology. 1980 Jun;27(3):227-30.

PMID:7461597
Abstract

Endoscopic retrograde pancreatography (ERP) combined with pancreatic juice cytology, was performed in 14 patients with pancreatic carcinoma confirmed at subsequent laparotomy. ERP demonstrated duct abnormalities that were diagnosed as carcinoma in 86% of the cases and as suggestive of carcinoma in another 14%. Cytology was positive in 86% and suspicious in 7%. By combining both methods, all 14 carcinomas were correctly identified. Thus, in our hands, ERP and pancreatic juice cytology proved to be the most sensitive and reliable methods in detecting pancreatic carcinoma. On the basis of these promising results it is proposed that pancreatic juice cytology, which is a no-risk method, should be employed in all elderly patients with unexplained abdominal complaints, to screen them for early pancreatic carcinoma.

摘要

对14例经后续剖腹手术确诊为胰腺癌的患者进行了内镜逆行胰胆管造影(ERP)并结合胰液细胞学检查。ERP显示导管异常,其中86%的病例被诊断为癌,另有14%提示为癌。细胞学检查阳性率为86%,可疑率为7%。通过将两种方法结合,14例癌均被正确识别。因此,在我们的研究中,ERP和胰液细胞学检查被证明是检测胰腺癌最敏感和可靠的方法。基于这些令人鼓舞的结果,建议对所有有不明原因腹部不适的老年患者采用胰液细胞学检查,这是一种无风险的方法,用于筛查早期胰腺癌。

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